The link between migraine and cardiovascular disease is complex and involves overlapping mechanisms, such as endovascular disturbances. Challenges in measuring migraine, in distinguishing between causation and prediction, and in the understanding of clinical implications highlight the need for further research to guide treatment and cardiovascular risk assessment for the millions of individuals living with migraine.
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T.K. has received research grants from the Gemeinsamer Bundesausschuss (G-BA – Federal Joint Committee, Germany) and the Bundesministerium für Gesundheit (BMG – Federal Ministry of Health, Germany), and has received personal fees from BMJ, Eli Lilly and Company and Frontiers. P.R. has received research grants from the National Institutes of Health, Brigham and Women’s Hospital and the American Heart Association (AHA), and has received personal compensation from the AHA for editorial work.
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Kurth, T., Rist, P.M. Migraines and cardiovascular disease: mechanisms and methodological challenges. Nat Rev Cardiol 20, 791–792 (2023). https://doi.org/10.1038/s41569-023-00934-7
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DOI: https://doi.org/10.1038/s41569-023-00934-7