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DNA nanomachines

Powering a DNA origami nanoengine with chemical fuel

A biohybrid, leaf-spring design of DNA origami functions as a pulsating nanoengine that exploits the DNA-templated RNA transcription mechanism while consuming nucleoside triphosphates as fuel. The nanoengine also drives a nanomechanical follower structure.

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Fig. 1: DNA nanoengine mechanics.

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Correspondence to Divita Mathur.

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Mathur, D. Powering a DNA origami nanoengine with chemical fuel. Nat. Nanotechnol. 19, 143–144 (2024). https://doi.org/10.1038/s41565-023-01573-2

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