A DNA origami nanoturbine is designed as a rotary motor that draws power from an ion gradient or electrical potential across a solid-state nanopore. Single-molecule experiments demonstrate that the turbine can drive a DNA bundle into sustained unidirectional rotation, with the preferred rotation direction set by the chirality of the turbine.
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References
Kassem, S. et al. Artificial molecular motors. Chem. Soc. Rev. 46, 2592–2621 (2017). A review article that presents artificial molecular motors.
Ramezani, H. & Dietz, H. Building machines with DNA molecules. Nat. Rev. Genet. 21, 5–26 (2020). A review article that presents the construction of nanoscale machines using DNA techniques.
Courbet, A. et al. Computational design of mechanically coupled axle-rotor protein assemblies. Science 376, 383–390 (2022). This paper reports de novo designed rotary proteins.
Maffeo, C., Quednau, L., Wilson, J. & Aksimentiev, A. DNA double helix, a tiny electromotor. Nat. Nanotechnol. 18, 238–242 (2023). This paper reports molecular dynamics simulations that show that a single DNA double helix can function as a nanomotor.
Shi, X. et al. Sustained unidirectional rotation of a self-organized DNA rotor on a nanopore. Nat. Phys. 18, 1105–1111 (2022). This paper reports self-organized DNA rotors on nanopores.
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This is a summary of: Shi, X. et al. A DNA turbine powered by a transmembrane potential across a nanopore. Nat. Nanotechnol. https://doi.org/10.1038/s41565-023-01527-8 (2023).
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Nanoturbine driven by flow across a nanopore. Nat. Nanotechnol. 19, 279–280 (2024). https://doi.org/10.1038/s41565-023-01532-x
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DOI: https://doi.org/10.1038/s41565-023-01532-x