Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Nanomedicine

Intracerebral fate of engineered nanoparticles

Organic and inorganic nanoparticles have different clearance mechanisms from the brain resulting in different biological fates and retention times.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Nanoparticle fates in the brain.

References

  1. Nance, E., Pun, S. H., Saigal, R. & Sellers, D. L. Nat. Rev. Mater. 7, 314–331 (2022).

    Article  CAS  PubMed  Google Scholar 

  2. Gao, J. et al. Nat. Nanotechnol. https://doi.org/10.1038/s41565-023-01551-8 (2023).

  3. Lojk, J., Repas, J., Veranic, P., Bregar, V. B. & Pavlin, M. Toxicology 432, 152364 (2020).

    Article  CAS  PubMed  Google Scholar 

  4. Hawkins, S. J. et al. Nat. Nanotechnol. 13, 427–433 (2018).

    Article  CAS  PubMed  Google Scholar 

  5. Iliff, J. J. et al. Sci. Transl. Med. 4, 147ra111 (2012).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Butovsky, O. & Weiner, H. L. Nat. Rev. Neurosci. 19, 622–635 (2018).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Elizabeth Nance.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nance, E. Intracerebral fate of engineered nanoparticles. Nat. Nanotechnol. 19, 273–274 (2024). https://doi.org/10.1038/s41565-023-01531-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41565-023-01531-y

Search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research