Recent improvements in de novo protein design are likely to support a broad range of applications, but larger complexes will be easier to create if a building block approach is adopted. Now protein filaments with tunable geometry can be made using assemblies that have both cyclic and superhelical symmetries aligned along the same axis.
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Tame, J.R.H. Using symmetry to drive new protein assemblies. Nat. Chem. 15, 1653–1654 (2023). https://doi.org/10.1038/s41557-023-01369-w
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DOI: https://doi.org/10.1038/s41557-023-01369-w
