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Neural stimulation

Optogenetic control of β cell function

Nature Biomedical Engineering (2023)Cite this article

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The optogenetic stimulation of pancreatic cholinergic signalling in insulin-deficient mice enhances the glucose-stimulated secretion of insulin and β cell proliferation.

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Fig. 1: Increasing β cell insulin release, as well as β cell proliferation, via the activation of pancreatic cholinergic nerves.

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Authors and Affiliations

  1. Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine, New York, NY, USA

    Maria Jimenez-Gonzalez & Sarah Stanley

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  1. Maria Jimenez-Gonzalez
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  2. Sarah Stanley
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Correspondence to Sarah Stanley.

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The authors declare no competing interests.

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Jimenez-Gonzalez, M., Stanley, S. Optogenetic control of β cell function. Nat. Biomed. Eng (2023). https://doi.org/10.1038/s41551-023-01125-y

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