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DRUG DELIVERY

A new opening for orally taken peptide drugs

Nature Biomedical Engineering volume 4, pages 12–13 (2020)Cite this article

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Negatively charged nanoparticles of about 50 nm in size permit the oral delivery of insulin and other peptide drugs by temporally enhancing the permeability of the intestinal wall.

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Fig. 1: Mechanisms of tight junction opening for enhancing the permeability of the intestinal wall.

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Authors and Affiliations

  1. Department of Pharmacy, Uppsala University, Uppsala, Sweden

    Per Artursson & Patrik Lundquist

  2. Science for Life Laboratory, Uppsala University, Uppsala, Sweden

    Per Artursson

Authors
  1. Per Artursson
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  2. Patrik Lundquist
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Correspondence to Per Artursson.

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The authors declare no competing interests.

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Artursson, P., Lundquist, P. A new opening for orally taken peptide drugs. Nat Biomed Eng 4, 12–13 (2020). https://doi.org/10.1038/s41551-019-0513-1

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