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IMMUNOTHERAPY

Inflammation-targeted vascular nanomedicine

Lipoprotein nanoparticles delivering an inflammation-targeting signalling inhibitor reduce vascular inflammation in atherosclerotic mice.

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Fig. 1: Reduction of atherosclerosis by a targeted nanoimmunotherapy.

References

  1. Smith, S. C. Jr et al. J. Am. Coll. Cardiol. 58, 2432–2446 (2011).

    Article  PubMed  Google Scholar 

  2. Cooke, J. P. Methodist Debakey Cardiovasc. J. 3, 154–155 (2015).

    Article  Google Scholar 

  3. Franck, G. et al. Circ. Res. 12, 31–42 (2017).

    Article  CAS  Google Scholar 

  4. Ridker, P. M. et al. N. Engl. J. Med. 377, 1119–1131 (2017).

    Article  PubMed  CAS  Google Scholar 

  5. Ridker, P. M. Circ. Res. 118, 145–156 (2016).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  6. Skajaa, T. et al. Arterioscler. Thromb. Vasc. Biol. 30, 169–176 (2010).

    Article  PubMed  CAS  Google Scholar 

  7. Tang, J. et al. Circulation 124, A9601 (2011).

    Google Scholar 

  8. Lameijer, M. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-018-0221-2 (2018).

  9. Libby, P., Ridker, P. M. & Hansson, G. K. J. Am. Coll. Cardiol. 54, 2129–2138 (2009).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  10. Seijkens, T. T. P. et al. J. Am. Coll. Cardiol. 71, 527–542 (2018).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  11. Cole, J. E. et al. Proc. Natl Acad. Sci. USA 108, 2372–2377 (2011).

    Article  PubMed  Google Scholar 

  12. Sayed, N. et al. Circulation 131, 300–309 (2015).

    Article  PubMed  CAS  Google Scholar 

  13. Buxton, D. B. et al. Circulation 108, 2737–2742 (2003).

    Article  PubMed  Google Scholar 

Download references

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Correspondence to Mauro Ferrari.

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Cooke, J.P., Ferrari, M. Inflammation-targeted vascular nanomedicine. Nat Biomed Eng 2, 269–270 (2018). https://doi.org/10.1038/s41551-018-0241-y

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