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Biological techniques

Measuring open chromatin and DNA methylation in repeat arrays

Nature Plants volume 9, pages 1379–1380 (2023)Cite this article

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Highly repetitive regions such as centromeres bedevilled genome assembly for decades until a recent flurry of gapless genome publications. Attention is now focused on interpreting the chromatin within these most repetitive regions, as illustrated by a new paper on simultaneously measuring open chromatin and DNA methylation using long-read sequencing.

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Fig. 1: Summary of the STAM-seq method.

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  1. Department of Plant Biology, University of Georgia, Athens, GA, USA

    R. Kelly Dawe

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  1. R. Kelly Dawe
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Correspondence to R. Kelly Dawe.

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The author declares no competing interests.

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Dawe, R.K. Measuring open chromatin and DNA methylation in repeat arrays. Nat. Plants 9, 1379–1380 (2023). https://doi.org/10.1038/s41477-023-01512-y

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