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GENE SILENCING

Tough GC beats transgene silencing

Solid genetic and genomic data now reveal that high guanine–cytosine content can prevent transgenes from RNA silencing, and enhance expression and transgenerational stability.

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Fig. 1: A high GC content protects transgenes from transposon-like silencing, enhances expression and maintains transgenerational stability.

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Correspondence to Xiuren Zhang.

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Zhang, X. Tough GC beats transgene silencing. Nature Plants 3, 850–851 (2017). https://doi.org/10.1038/s41477-017-0048-y

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