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Does the degree of preoperative gait disturbance remain after tumor resection in patients with intradural extramedullary spinal cord tumors?

Spinal Cord volume 61, pages 637–643 (2023)Cite this article

Subjects

Abstract

Study design

Retrospective comparative study.

Objective

This study aimed to determine whether the degree of preoperative gait disturbance remains following surgical resection in patients with intradural extramedullary spinal cord tumors (IDEMSCTs), and to investigate any factors that may influence poor improvement in postoperative gait disturbance.

Setting

The single institution in Japan.

Methods

In total, 78 IDEMSCTs patients who required surgical excision between 2010 and 2019 were included. According to the degree of preoperative gait disturbance using modified McCormick scale (MMCS) grade, they were divided into the Mild and Severe groups. The mean postoperative follow-up period was 50.7 ± 17.9 months. Data on demographic and surgical characteristics were compared between the two groups.

Results

There was no significant difference in terms of age at surgery, sex, tumor size, surgical time, estimated blood loss, tumor histopathology, and postoperative follow-up period between the Mild and Severe groups. At the final follow-up, 84.6% of IDEMSCTs patients were able to walk without support. Gait disturbance improved after surgery in most of the patients with preoperative MMCS grades II–IV, but remained in approximately half of patients with preoperative MMCS grade V. Age at surgery was correlated with poor improvement in postoperative gait disturbance in the Severe group.

Conclusions

Regardless of the degree of preoperative gait disturbance, it improved after tumor resection in most of the IDEMSCTs patients. However, in the preoperative MMCS grade III–V cases, older age at surgery would be an important factor associated with poor improvement in postoperative gait disturbance.

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Data availability

The datasets generated and/or analyzed in this study are available from the corresponding author on request.

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Acknowledgements

The authors would like to thank Enago (www.enago.jp) for the English language review.

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Authors and Affiliations

  1. Department of Orthopaedics Surgery, National Hospital Organization, Murayama Medical Center, Tokyo, Japan

    Toshiki Okubo, Kanehiro Fujiyoshi, Yoshiomi Kobayashi, Kohei Matsubayashi, Tsunehiko Konomi, Mitsuru Furukawa, Takashi Asazuma & Yoshiyuki Yato

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  1. Toshiki Okubo
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Contributions

TO collected and interpreted the data, and wrote the initial draft of this manuscript. KF, YK, and KM assisted in the preparation of the manuscript. TO designed the study, and TK, MF, TA, and YY critically reviewed the manuscript. All authors approved the final version of the manuscript and agreed to be accountable for all aspects of the work to ensure that questions associated with the accuracy or integrity of any part of the work were appropriately evaluated and resolved.

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Correspondence to Toshiki Okubo.

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Okubo, T., Fujiyoshi, K., Kobayashi, Y. et al. Does the degree of preoperative gait disturbance remain after tumor resection in patients with intradural extramedullary spinal cord tumors?. Spinal Cord 61, 637–643 (2023). https://doi.org/10.1038/s41393-023-00931-0

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