Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Review Article
  • Published:

Bariatric Surgery

Exploring pre-surgery and post-surgery substance use disorder and alcohol use disorder in bariatric surgery: a qualitative scoping review

A Correction to this article was published on 11 September 2019

Abstract

Introduction

Bariatric surgery (BS) produces superior weight loss compared to non-surgical interventions. However, studies suggest bariatric patients who have undergone gastric-bypass surgery have an increased risk of developing new onset substance use disorder (SUD) or suffer negative outcomes after surgery. As such, many bariatric programs consider alcohol/ illicit drug misuse a contraindication to BS. The purpose of this systematic review was to investigate weight loss outcomes, post-surgery substance use patterns and other morbidity/mortality in BS patients with a history of substance use/SUD.

Methods

Studies were identified by searching Ovid Medline(R), Embase, and PsychInfo. We included all study types investigating humans of any age/sex who had undergone any BS procedure with data regarding substance use before and/or after surgery. Outcome measures included metabolic outcomes and psychiatric outcomes after bariatric surgery in patients reporting substance use prior to bariatric surgery and substance use patterns after bariatric surgery.

Results

Fifty-eight studies were included in the review. Studies reporting weight loss after BS did not demonstrate an association between substance use and negative weight loss outcomes. Several studies reported a significant portion of participants having new onset or increased substance use after BS. Factors associated with new onset or increased substance use/SUD after BS included the type of surgery, a history of SUD, a family history of SUD, coping skills/life stressors, age, male sex and alcohol sensitization after surgery.

Conclusion

Substance use history does not appear to influence weight loss after BS, however it may contribute to increased substance use after BS. Clinicians should ensure valid screening tools when assessing BS candidates for substance use history and ensure long term follow-up care post-operatively.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1

Similar content being viewed by others

References

  1. Sheets CS, Peat CM, Berg KC, White EK, Bocchieri-Ricciardi L, Chen EY, et al. Post- operative psychosocial predictors of outcome in bariatric surgery. Obes Surg. 2015;25:330–45.

    Article  Google Scholar 

  2. Dawes AJ, Maggard-Gibbons M, Maher AR, Booth MJ, Miake-Lye I, Beroes JM, et al. Mental health conditions among patients seeking and underoing bariatric surgery. JAMA. 2016;315:150–63.

    Article  CAS  Google Scholar 

  3. Parikh M, Johnson JM, Ballem N. ASMBS position statement on alcohol use before and after bariatric surgery. Surg Obes Relat Dis. 2016;12:225–30.

    Article  Google Scholar 

  4. Taylor VH. Weighty matters: the association between mental health, pregnancy, and obesity. J Popul Ther Clin Pharmacol. 2012;19:e483–7.

    PubMed  Google Scholar 

  5. Oprah.com, “Suddenly Skinny”. 10/24/2006, http://www.oprah.com/oprahshow/suddenly-skinny/all%20accessed%20December%2013.Accessed Dec 2017.

  6. Spadola CE, Wagner EF, Dilon FR, Trepka MJ, Cruz-Munoz N, Messiah SE. Alcohol and drug use among postoperative bariatric patients: a systematic review of the emerging research and its implications. Alcohol Clin Exp Res. 2015;39:1582–601.

    Article  Google Scholar 

  7. Heinberg LJ, Ashton K, Coughlin J. Alcohol and bariatric surgery: review and suggested recommendations for assessment and management. Surg Obes Relat Dis. 2012;8:357–63.

    Article  Google Scholar 

  8. Steffen KJ, Engel SG, Wonderlich JA, Pllert GA, Sondag C. Alcohol and other addictive disorders following bariatric surgery, risk factors and possible etiologies. Eur Eat Disord Rev. 2015;23:442–50.

    Article  Google Scholar 

  9. Li L, Wi L. Substance use after bariatric surgery: A review. J Psychiatr Res. 2016;76:16–29.

    Article  Google Scholar 

  10. Ali M, El Chaar M, Ghiassi S, Rogers AM. American society for metabolic and bariatric surgery updated position statement on sleeve gastrectomy as a bariatric procedure. Surg Obes Relat Dis. 2017;13:1652–57.

    Article  Google Scholar 

  11. Thomas BH, Ciliska D, Dobbins M, Micucci S. A process for systematically reviewing the literature: providing the research evidence for public health nursing interventions. Worldviews Evid Based Nurs. 2004;1:176–84.

    Article  CAS  Google Scholar 

  12. Burgos MG, Cabral PC, Maio R, Oliveira BM, Dias MS, Melim DB, et al. Prevalence of alcohol abuse before and after bariatric surgery associated with nutritional and lifestyle factors: a study involving a portuguese population. Obes Surg. 2015;25:1716–22.

    Article  Google Scholar 

  13. Mitchell JE, Steffen K, Engel S, King WC, Chen JY, Winters K, et al. Addictive disorders after Roux-En-Y gastric bypass. Surg Obes Relat Dis. 2015;11:897–905.

    Article  Google Scholar 

  14. Tedesco M, Hua WQ, Lohnberg JA, Bellatorre N. A Prior History of Substance Abuse in Veterans Undergoing Bariatric Surgery.” J Obes. 2013; 740312.

  15. Lent MR, Hayes SM, Wood GC, Napolitano MA, Argyropoulos G, Gerhard GS, et al. Smoking and alcohol use in gastric bypass patients. Eat Behav. 2013;14:460–3.

    Article  Google Scholar 

  16. Sanchez-Cabezudo Diaz-Guerra C, Larrad Jimenez A. Analysis of weight loss with the biliopancreatic diversion of larrad: absolute failures or relative successes? Obes Surg. 2002;12:249–52.

    Article  Google Scholar 

  17. Yanos BR, Saules KK, Schuh LM. Predictors of lowest weight and long-term weight regain among roux-en-y gastric bypass patients. Obes Surg. 2015;25:1364–70.

    Article  Google Scholar 

  18. Odom J, Zalesin KC, Washington TL, Miller WW, Hakmeh B, Zaremba DL, et al. Behavioral predictors of weight regain after bariatric surgery. Obes Surg. 2010;20:349–56.

    Article  Google Scholar 

  19. Vidot DC, Prado G, De La Cruz-Munoz N, Spadola C, Cuesta M. Postoperative marijuana use and disordered eating among bariatric surgery patients. Surg Obes Relat Dis. 2016;12:171–8.

    Article  Google Scholar 

  20. Adams CE, Gabriele JM, Baillie LE. Tobacco use and substance use disorders as predictors of postoperative weight loss 2 years after bariatric surgery. J Behav Health Serv Res. 2012;39:462–71.

    Article  Google Scholar 

  21. Kalarchian MA, Marcus MD, Levine MD, Soulakova JN, Courcoulas AP. Relationship of psychiatric disorders to 6-Month outcomes after gastric bypass. Surg Obes Relat Dis. 2008;4:544–9.

    Article  Google Scholar 

  22. Marek RJ, Tarescavage AM, Ben-Porath YS, Ashton K, Merrell RJ, Heinberg LJ. Using presurgical psychological testing to predict 1-Year appointment adherence and weight loss in bariatric surgery patients: predictive validity and methodological considerations. Surg Obesity Relat Dis. 2015;11:1171–81.

    Article  Google Scholar 

  23. Hayden MJ, Murphy KD, Brown WA. Axis I disorders in adjustable gastric band patients: the relationship between psychopathology and weight Loss. Obes Sug. 2014;24:1469–75.

    Article  CAS  Google Scholar 

  24. Kalarchian MA, King WC, Devlin MJ, Marcus MD, Garcia L, Chen JY, et al. Psychiatic disorders and weight change in a prospective study of bariatric surgery patients: a 3-year follow-up. Psychosom. Med. 2016;78:373–81.

    Article  Google Scholar 

  25. Pulcini ME, Saules KK. Roux-en-y gastric bypass patients hospitalized for substance use disorders achieve successful weight loss despite poor psychosocial outcomes. Clin Obes. 2013;3:95–102.

    Article  CAS  Google Scholar 

  26. Marek RJ, Ben-Porath YS, van Dulmen M, Ashton K, Heinberg HJ. Using the presurgical psychological evaluation to predict 5-year weight loss outcomes in bariatric surgery patients. Surg Obes Relat Dis. 2017;13:514–21.

    Article  Google Scholar 

  27. Reslan S, Saules KK, Greenwald MK. Substance misuse following roux-en-y gastric bypass surgery. Subst Use Misuse. 2014;49:405–17.

    Article  Google Scholar 

  28. Heinberg LJ, Ashton K. History of substance abuse relates to improved postbariatric body mass index outcomes. Surg Obes Relat Dis. 2010;6:417–21.

    Article  Google Scholar 

  29. Clark MM, Balsiger BM, Sletten CD, Dahlman KL, Ames G, Williams DE, et al. Psychosocial factors and 2-year outcome following bariatric surgery for weight loss. Obes Surg. 2003;13:739–45.

    Article  Google Scholar 

  30. Conason A, Teixeira J, Hsu CH, Puma L, Knafo D. Substance use following bariatric weight loss surgery. JAMA Surg. 2013;148:145–50.

    Article  Google Scholar 

  31. King WC, Chen JY, Mitchell JE, Kalarchian MA, Steffen KJ, Engel SG, et al. Prevalence of alcohol use disorders before and after bariatric surgery. JAMA. 2012;307:2516–25.

    Article  CAS  Google Scholar 

  32. King WC, Chen JY, Courcoulas AP, Dakin GF, Engel SG, Flum DR, et al. Alcohol and other substance use after bariatric surgery: prospective evidence from a US multicenter cohort study. Surg Obes Relat Dis. 2017;13:1392–404.

    Article  Google Scholar 

  33. Kovacs Z, Valentin JB, Nielsen RE. Risk of psychiatric disorders, self-harm behavior and service use associated with bariatric surgery. Acta Psychiatre Scand. 2017;135:149–58.

    Article  CAS  Google Scholar 

  34. Suzuki J, Haimovici F, Chang G. Alcohol use disorders after bariatric surgery. Obes Surg. 2012;22:201–7.

    Article  Google Scholar 

  35. Smith KE, Engel SG, Steffen KJ, Garcia L, Grothe K, Koball A, et al. Problematic alcohol use and associated characteristic following bariatric surgery. Obes Surg. 2018;28:1248–54.

    Article  Google Scholar 

  36. Wiedemann AA, Saules KK, Ivezaj V. Emergence of new onset substance use disorders among post-weight loss surgery patients. Clin Obes. 2013;3:194–201.

    Article  CAS  Google Scholar 

  37. Cuellar-Barboza AB, Frye MA, Grothe K, Prieto ML, Schneekloth TD, Loukianova LL, et al. Change in consumption patterns for treatment-seeking patients with alcohol use disorder post-bariatric surgery. J Psychosom Res. 2015;78:199–204.

    Article  Google Scholar 

  38. Saules KK, Wiedemann A, Ivezaj V, Hopper JA, Foster-Hartsfield J. Bariatric surgery history among substance abuse treatment patients: prevalence and associated features. Surg Obes Relat Dis. 2010;6:615–21.

    Article  Google Scholar 

  39. Backman O, Stockeld D, Rasmussen F, Naslund E, Marsk R. Alcohol and substance abuse, depression and suicide attempts after roux-en-y gastric bypass surgery. BJS. 2016;103:1336–42.

    Article  CAS  Google Scholar 

  40. Gribsholt SB, Svensson E, Richelsen B, Raundahl U, Sorensen HT, Thomsen RW. Rate of acute hospital admissions before and after roux-en-y gastric bypass surgery. Ann. Surg. 2018;267:319–25.

    Article  Google Scholar 

  41. Spadola CE, Wagner EF, Accornero VH, Vidot DC, Cruz-Munoz NF, Messiah SE. Alcohol use patterns and alcohol use disorders among young adult, ethnically diverse bariatric surgery patients. Subst Abus. 2017;38:82–87.

    Article  Google Scholar 

  42. Ivezaj V, Saules KK. New-onset substance use disorder after gastric bypass surgery: rates and associated characteristics. Obe Surg. 2014;24:1975–80.

    Article  Google Scholar 

  43. Bhatti JA, Nathens AB, Thiruchelvan D, Redelmeier DA. Weight loss surgery and subsequent emergency care use: a population-based cohort study. Am J. Emerg Med. 2016;34:861–5.

    Article  Google Scholar 

  44. Zeller MH, Washington GA, Mitchell JE, Sarwer DB, Reiter-Purtill J, Jenkins TM, et al. Alcohol use risk in adolescents 2 years after bariatric surgery. Surg Obes Relat Dis. 2017;13:85–94.

    Article  Google Scholar 

  45. Wendling A, Wudyka A. Narcotic addiction following gastric bypass surgery-a case study. Obes Surg. 2011;21:680–3.

    Article  Google Scholar 

  46. Higa KD, Ho T, Boone KB, Roubicek MC. Narcotic withdrawal syndrome following gastric bypass - a difficult diagnosis. Obes Surg. 2001;11:631–4.

    Article  CAS  Google Scholar 

  47. Fogger SA, McGuinness TM. The Relationship between addictions and bariatric surgery for nurses in recovery. Perspect Psychiatr Care. 2012;48:10–5.

    Article  Google Scholar 

  48. Ostlund MP, Backman O, Marsk R, Stockeld D, Lagergren J, Rasmussen F, et al. Increased admission for alcohol dependence after gastric bypass surgery compared with restrictive bariatric surgery. JAMA Surg. 2013;148:374–7.

    Article  Google Scholar 

  49. Svensson PA, Anveden A, Romeo S, Peltonen M, Ahlin S, Burza MA, et al. Alcohol consumption and alcohol problems after bariatric surgery in the swedish obese subjects study. Obesity. 2013;21:2444–51.

    Article  Google Scholar 

  50. Raebel MA, Newcomer SR, Bayliss EA, Boudreau D, DeBar L, Elliott TE, et al. Chronic opioid use emerging after bariatric surgery. Pharmacoepidemiol Drug Saf. 2014;23:1247–57.

    Article  Google Scholar 

  51. Spadola CE, Wagner EF, Varga LM, Syvertsen JL, Cruz-Munoz NF, Messiah SE. A qualitative examination of increased alcohol use after bariatric surgery among racially/ethnically diverse young adults. Obes Surg. 2018;12:1492–7.

    Article  Google Scholar 

  52. Yoder R, MacNeela P, Conway R, Heary C. How do individuals develop alcohol use disorder after bariatric surgery? A grounded theory explanation. Obes Surg. 2018;28:717–24.

    Article  Google Scholar 

  53. Zeller MH, Pendery EC, Reiter-Purtill J, Hunsaker SL, Jenkins TM, Helmrath MA, et al. From adolescence to young adulthoot: trajectories of psychosocial health following roux-en-y gastric bypass. Surg Obes Relat Dis. 2017;13:1196–203.

    Article  Google Scholar 

  54. Fowler L, Ivezaj V, Saules KK. Problematic intake of high-sugar/low-fat and high glycemic index foods by bariatric patients is associated with development of post-surgical new onset substance use disorders. Eat Behav. 2014;15:505–8.

    Article  Google Scholar 

  55. Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG. The alcohol use disorders identification test, guidelines for use in primary care. World Health Organization, Department of Mental Health and Substance Dependence. 2001 2nd edition, 10–11.

  56. Westermeyer J, Yargic I, Thuras P. Michigan assessment-screening test for alcohol and drugs (MAST/AD): evaluation in a clinical sample. Am J Addict. 2012;12:151–62.

    Google Scholar 

  57. WHO ASSIST Working Group. The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST): development, reliability and feasibility. Addiction. 2002;97:1183–94.

    Article  Google Scholar 

  58. Watkins BJ, Blackmun S. Gastric adenocarcinoma after roux-en-y gastric bypass: access and evaluation of excluded stomach. Surg Obes Relat Dis. 2007;3:644–7.

    Article  Google Scholar 

  59. Still CD, Wood GC, Chu X, Manney C, Strodel W, Petrick A, et al. Clinical factors associated with weight loss outcomes after roux-en-y gastric bypass surgery. Obesity. 2014;22:888–94.

    Article  Google Scholar 

  60. Talem DA, Talamini M, Gesten F, Patterson W, Peoples B, Gracia G, et al. Hospital admissions greater than 30 days following bariatric surgery: patient and procedure matter. Surg Endosc. 2015;29:1310–5.

    Article  Google Scholar 

  61. Diniz Mde F, Moura LD, Kelles SM, Diniz MT. Long-term mortality of patients submitted to roux-en-y gastric bypass in public health system: high prevalence of alcoholic cirrhosis and suicides. Arq Bras de Cir Dig. 2013;26(Suppl 1):53–6.

    Article  Google Scholar 

  62. Totte E, Hendrickx L, Van Hee R. Biliopancreatic diversion for treatment of morbid obesity: experience in 180 consecutive cases. Obes Surg. 1999;9:161–5.

    Article  CAS  Google Scholar 

  63. Ortega J, Fernandez-Canet R, Alvarez-Valdeita S, Cassinello N. Predictors of psychological symptoms in morbidly obese patients after gastric bypass surgery. Surg Obes Relat Dis. 2012;8:770–6.

    Article  Google Scholar 

  64. Nandipati K, Lin E, Husain F, Perez S, Srinivasan J, Sweeney JF. Factors predicting the increased risk for return to the operating room in bariatric patients: A NSQIP database study. Surg Endos. 2013;27:1172–7.

    Article  Google Scholar 

  65. Nakamura KM, Haglind EG, Clowes JA, Achenbach SJ, Atkinson EJ, Melton LJ. Fracture risk following bariatric surgery: A population-based study. Osteoporos Int. 2014;25:151–8.

    Article  CAS  Google Scholar 

  66. Benotti P, Wood GC, Winegar DA, Petrick AT, Still CD, Argyropoulos G, et al. Risk factors associated with mortality after roux-en-y gastric bypass surgery. Ann Surg. 2014;259:123–30.

    Article  Google Scholar 

  67. Brolin RE, Asad M. Rationale for reversal of failed bariatric operations. Surg Obes Relat Dis. 2009;5:673–6.

    Article  Google Scholar 

  68. Segal A, Hilton Libanori HT, Azevedo A. Bariatric surgery in a patient with possible psychiatric contraindications. Obes Surg. 2002;12:598–601.

    Article  Google Scholar 

  69. Ivezaj V, Saules KK, Wiedemann AA. I didn’t see this coming: why are postbariatric patients in substance abuse treatment? Patients’ perceptions of etiology and future recommendations. Obes Surg. 2012;22:1308–14.

    Article  Google Scholar 

  70. Dutta S, Morton J, Shepard E, Peebles R, Farrales-Nguyen S, Hammer LD. Methamphetamine use following bariatric surgery in an adolescent. Obes Surg. 2006;16:780–2.

    Article  Google Scholar 

  71. Ramanan B, Gupta PK, Gupta H, Fang X. Development and validation of a bariatric surgery mortality risk calculator. J Am Coll Surg. 2012;214:892–900.

    Article  Google Scholar 

  72. Signorini FJ, Polero V, Viscido G, Navarro L, Obeide L, Moser F. Long-term relationship between tobacco use and weight loss after sleeve gastrectomy. Obes Surg. 2018;28:2644–49.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to V. H. Taylor.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary information

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kanji, S., Wong, E., Akioyamen, L. et al. Exploring pre-surgery and post-surgery substance use disorder and alcohol use disorder in bariatric surgery: a qualitative scoping review. Int J Obes 43, 1659–1674 (2019). https://doi.org/10.1038/s41366-019-0397-x

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41366-019-0397-x

This article is cited by

Search

Quick links