Abstract
Aim: To evaluate whether strict aseptic procedures reduces the CONS positive blood cultures.
Methods: In our neonatal unit, any procedure involving skin breakdown is done in a sterile aseptic procedure (from 1st September 2008). We analysed all positive blood cultures from the neonatal unit from November 2007 to October 2009 (10 months before the intervention and 13 months after). We analysed the positive blood cultures in relation to the number of admissions in the unit and the Intensive care/High dependency activity in the neonatal unit in the same month. Statistical analysis was using two sample independent âtâ test.
Results: The number of CONS positive cultures reduced by 75% in the first 3 months and 40-50% in the subsequent 10 months. (p 0.008, 95% CI (0.75 -4.45). There was reduction in the CONS positive cultures in relation to the number of admissions (p 0.025, 95% CI (0.45 -7.1). In relation to the Intensive care/High dependency activity, there was a 70-80% reduction in the CONS positive cultures in the first 3 months and 40-50% reduction in the latter 10 months. (p 0.01, 95%CI (0.21-1.48).
Conclusion: CONS is a common nosocomial infection in the neonatal unit. Our incidence is about 7-10/1000 live births (some could be contamination without infection). There was reduction in the number of positive CONS post introduction of above precautions and the reduction was also seen in relation to the number of admissions and to ITU/ HDU activity. However, they need to be monitored regularly and kept under strict surveillance.
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Venugopalan, V. 1378 Current Strategies to Reduce Coagulase Negative Staphylococcus (CONS) in the Neonatal Unit. Pediatr Res 68 (Suppl 1), 682 (2010). https://doi.org/10.1203/00006450-201011001-01378
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DOI: https://doi.org/10.1203/00006450-201011001-01378