Abstract
We have identified a family in which typical EI developed in an epidemic setting in four male siblings and their father. Three individuals who were HLA-B27+ developed arthritis (Figure). Two nine year old twins developed joint pains and morning stiffness five days after the onset of rash and fever, and one of these has continued to have small joint arthritfs of his hands and feet. Their father also became febrile and subsequently developed low back pain and joint stiffness. The ANA and RF were negative. Two other children with EI who Were HLA-B27- had no arthritis. Human parvovirus has been shown to be the likely etiologic agent of EI. Our observations suggest that one form of arthropathy in EI has features in common with reactive arthritis, and occurs in genetically susceptible individuls
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Logalbo, P., Solomon, G. & Winchester, R. OCCURENCE OF ARTHRITIS FOLLOWING ERYTHEMA INFECTIOSUM(EI) IN HLA-B27+ MEMBERS OF A FAMILY. Pediatr Res 21 (Suppl 4), 314 (1987). https://doi.org/10.1203/00006450-198704010-00879
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DOI: https://doi.org/10.1203/00006450-198704010-00879