Abstract
97 peripheral venous lines (PVL) were prospectively studied to determine 1) if the infiltration incidence differs for 10% dextrose (D) vs 10% dextrose/amino acid solutions (DAA) and 2) if the continuous infusion of fat emulsion concurrently with dextrose/amino acid solutions (DAAF) affects the incidence or time to infiltration, The patients had a mean age ± SD of 2.1 ± 2.9 months (range:0.03-12). 34 patients received (D), 30 (DAA)7 and 33 (DAAF). Electrolyte and mineral content was standardized for the DAA and DAAF groups. All solutions were infused via teflon catheters with similar gauge. The three groups were similar with respect to age, race, gender, weight, and site (p>0.05). Patients receiving DAA and DAAF had higher infusion rates than the D group (p<0.001). 70% of D, 66% of DAA and 67% of DAAF infiltrated (p>0.05). The probability of infiltration was significantly different with DAA > than D or DAAF (p=0.01).
No complications were noted following infiltration of any solution. We conclude: 1) there is a significant difference in the time to and probability of infiltration when DAA are infused, and 2) continuous infusion of fat emulsion with DAA significantly prolongs the survival of a PVL.
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Phelps, S., Cochran, E. & Kamper, C. PERIPHERAL VENOUS LINE INFILTRATION IN INFANTS RECEIVING 10% DEXTROSE, 10% DEXTROSE/AMINO ACIDS, OR 10% DEXTROSE/AMINO ACIDS/FAT EMULSION. Pediatr Res 21 (Suppl 4), 286 (1987). https://doi.org/10.1203/00006450-198704010-00713
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DOI: https://doi.org/10.1203/00006450-198704010-00713