Abstract
We defined 218 children at high risk for otitis media (OM) in that each had received myringotomy with tympanostomy-tube placement (M & T) and, subsequent to tube extrusion, had developed recurrent acute or secretory OM. 102 children were assigned to an adenoidectomy or control group randomly, and 116 according to parental preference, and all were followed closely. Standardized antimicrobial regimens were used for new episodes of OM, as were specified criteria for repeat MST for persistent middle-ear effusion. Each ear of each subject on each follow-up day was categorized as with or without tube, and with or without OM.
Preliminary results in the random trial in subjects largely completing full years of follow-up were as follows:
In the nonrandom trial, results also tended to favor surgical subjects, but the differences were not statistically significant.
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Paradise, J., Bluestone, C., Rogers, K. et al. EFFICACY OF ADENOIDECTOMY FOR RECURRENT OTITIS MEDIA: RESULTS FROM PARALLEL RANDOM AND NONRANDOM TRIALS. Pediatr Res 21 (Suppl 4), 286 (1987). https://doi.org/10.1203/00006450-198704010-00711
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DOI: https://doi.org/10.1203/00006450-198704010-00711
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