Abstract
Pulmonary hemorrhage was the leading cause of perinatal mortality in the early 1970 (Fredrick and Butler 1971). However, the impact of improved perinatal care and the reduction in perinatal mortality during the last decade, upon PH has not been studied. We compared the incidence, distribution and the cause of PH for the two times periods (1974-1976 (I) vs 1983-1985(11)).
The incidence of PH and its distribution among b.wt, (500g) groups were significantly different for both periods (Chi-square 59.10, p<0.01). 24/43 (56%) in period I and 6/32 (19% in period II had massive pulmonary hemorrhage (MPH). The remaining 44 and 81% in period I and II respectively were diagnosed only at autopsy as focal interstitial and intra parenchymal hemorrhages.
We conclude that (1) while MPH was decreased significantly in the recent years, the autopsy evidence of PH remained same. (2) Significantly more number of tiny neonates (<29 wks gestation (59%) and <1.0kg (47%)) had PH in period II when compared to period I. (3) Hypothermia and sepsis were the major associated factor in period I than in period II (46.5 vs 9%, and 12.4 vs 6% (4))incidence of HMD, oxygen requirement were similar in both periods. We attribute the decreased incidence of massive pulmonary hemorrhage to the improved neonatal care during the last decade.
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Bhat, R., Ortega, R. CHANGING PATTERNS IN NEONATAL PULMONARY HEMORRHAGE (PH). Pediatr Res 21 (Suppl 4), 282 (1987). https://doi.org/10.1203/00006450-198704010-00690
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DOI: https://doi.org/10.1203/00006450-198704010-00690