This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Chemotherapy and tumor microenvironment of pancreatic cancer
Cancer Cell International Open Access 05 July 2017
Access options
Subscribe to this journal
Receive 50 print issues and online access
$259.00 per year
only $5.18 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Richards KE, Zeleniak AE, Fishel ML, Wu J, Littlepage LE, Hill R . Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells. Oncogene e-pub ahead of print 26 September 2016 doi:10.1038/onc.2016.353.
Namba T, Kodama R, Moritomo S, Hoshino T, Mizushima T . Zidovudine, an anti-viral drug, resensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine by inhibition of the Akt-GSK3beta-Snail pathway. Cell Death Dis 2015; 6: e1795.
Bonomi A, Sordi V, Dugnani E, Ceserani V, Dossena M, Cocce V et al. Gemcitabine-releasing mesenchymal stromal cells inhibit in vitro proliferation of human pancreatic carcinoma cells. Cytotherapy 2015; 17: 1687–1695.
Pascucci L, Cocce V, Bonomi A, Ami D, Ceccarelli P, Ciusani E et al. Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery. J Control Release 2014; 192: 262–270.
Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Nirodi CS et al. An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor kappaB- and hypoxia-inducible factor 1alpha-mediated up-regulation of CXCR4. J Biol Chem 2013; 288: 21197–21207.
Xu X, Tan X, Tampe B, Sanchez E, Zeisberg M, Zeisberg EM . Snail is a direct target of hypoxia-inducible factor 1alpha (HIF1alpha) in hypoxia-induced endothelial to mesenchymal transition of human coronary endothelial cells. J Biol Chem 2015; 290: 16653–16664.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no conflict of interest.
Rights and permissions
About this article
Cite this article
Suklabaidya, S., Dash, P. & Senapati, S. Pancreatic fibroblast exosomes regulate survival of cancer cells. Oncogene 36, 3648–3649 (2017). https://doi.org/10.1038/onc.2016.528
Published:
Issue Date:
DOI: https://doi.org/10.1038/onc.2016.528
This article is cited by
-
Statins abrogate gemcitabine-induced PD-L1 expression in pancreatic cancer-associated fibroblasts and cancer cells with improved therapeutic outcome
Cancer Immunology, Immunotherapy (2023)
-
Chemotherapy and tumor microenvironment of pancreatic cancer
Cancer Cell International (2017)