Advances in imaging have improved our understanding of the relationship between pathology and the structural changes to joints affected by osteoarthritis. New research indicates that subchondral bone marrow lesions might represent a potential imaging biomarker to quantify such structural changes.
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Acknowledgements
The author's work is supported by the NIH National Institute for Arthritis and Musculoskeletal and Skin Diseases (P60AR054731) University of Pittsburgh Multidisciplinary Clinical Research Center. The views expressed in this article are those of the author and not the Department of Veterans Affairs, for whom the author is Chief of Rheumatology in the Pittsburgh VA Healthcare System, Pittsburgh, PA, USA.
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C. K. Kwoh has acted as a consultant for Allergan, Novartis and Pfizer.
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Kwoh, C. Clinical relevance of bone marrow lesions in OA. Nat Rev Rheumatol 9, 7–8 (2013). https://doi.org/10.1038/nrrheum.2012.217
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DOI: https://doi.org/10.1038/nrrheum.2012.217
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