Sequential MRI assessment of 80 children during the first year after convulsive status epilepticus (CSE) has revealed that hippocampal injury not only occurs in the acute phase that immediately follows CSE, but may also progress over time. Contrary to previous assumptions, hippocampal volume loss could result from CSE of any aetiology, and was not limited to children with febrile seizures.
ORIGINAL RESEARCH PAPER
Yoong, M. et al. Hippocampal volume loss following childhood convulsive status epilepticus is not limited to prolonged febrile seizures. Epilepsia doi:10.1111/epi.12426
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Childhood convulsive status epilepticus may lead to progressive hippocampal volume loss. Nat Rev Neurol 9, 659 (2013). https://doi.org/10.1038/nrneurol.2013.237
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DOI: https://doi.org/10.1038/nrneurol.2013.237
