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Peripheral neuropathies

Biomarkers for axonal damage in immune-mediated neuropathy

Biomarkers are generally used as diagnostic and prognostic tools in clinical practice, but are not yet available for neuropathies. Studies now suggest that neural protein levels in serum and cerebrospinal fluid reflect axonal damage and predict poor outcome in patients with immune-mediated neuropathy, although validation studies are needed to define their clinical relevance.

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Correspondence to Bart C. Jacobs.

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Jacobs, B., Willison, H. Biomarkers for axonal damage in immune-mediated neuropathy. Nat Rev Neurol 5, 584–585 (2009). https://doi.org/10.1038/nrneurol.2009.161

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