Podocyte biologists can boast of some important advances in 2015. Some of the key developments include defining the transcriptional targets of the Wilms' tumour protein on a genome-wide scale, the identification of new mitochondria-centred pathways for maintaining podocyte homeostasis, and new insights into the regulation and pathogenic activation of TRPC6.
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Acknowledgements
The author thanks Ali Gharavi, Columbia University Medical Center, for helpful insights regarding the use of adriamycin in mice.
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J.H.M. declares no competing interests.
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Miner, J. New insights into the mechanisms of podocyte health. Nat Rev Nephrol 12, 63–64 (2016). https://doi.org/10.1038/nrneph.2015.204
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DOI: https://doi.org/10.1038/nrneph.2015.204
