In the past decade, major advances have been made in defining the antigens and pathogenesis of immune complex diseases such as membranous nephropathy and IgA nephropathy. Probing of rare genetic diseases has revealed new pathways of injury in proteinuric conditions, including channel abnormalities in the podocyte and complement dysregulation underlying proliferative glomerular lesions.
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Fogo, A. The glomerulus reveals some secrets. Nat Rev Nephrol 11, 633–634 (2015). https://doi.org/10.1038/nrneph.2015.149
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DOI: https://doi.org/10.1038/nrneph.2015.149
