2013 saw the publication of numerous studies that identified resident renal stem or progenitor cells, induced pluripotent stem cells and strategies based on stem cell paracrine action, which all might be suitable for kidney regeneration after injury.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Kidney-derived c-kit+ progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria
Scientific Reports Open Access 03 October 2018
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Rangel, E. B. et al. C-Kit+ cells isolated from developing kidneys are a novel population of stem cells with regenerative potential. Stem Cells 31, 1644–1656 (2013).
Bussolati, B. et al. Isolation of renal progenitor cells from adult human kidney. Am. J. Pathol. 166, 545–555 (2005).
Sagrinati, C. et al. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J. Am. Soc. Nephrol. 17, 2443–2456 (2006).
Harari-Steinberg, O. et al. Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease. EMBO Mol. Med. 5, 1556–1568 (2013).
Mae, S. et al. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat. Commun. http://dx.doi.org/10.1038/ncomms2378.
Fagoonee, S., Pellicano, R., Silengo, L. & Altruda, F. Potential applications of germline cell-derived pluripotent stem cells in organ regeneration. Organogenesis 7, 116–122 (2011).
De Chiara, L. et al. Renal cells from spermatogonial germline stem cells protect against kidney injury. J. Am. Soc. Nephrol. http://dx.doi.org/10.1681/ASN.2013040367.
Humphreys, B. D. et al. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell 2, 284–291 (2008).
Camussi, G. et al. Exosomes/microvesicles as a mechanism of cell-to-cell communication. Kidney Int. 78, 838–848 (2010).
Zhou, Y. et al. Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro. Stem Cell Res. Ther. http://dx.doi.org/10.1186/scrt194.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
G. Camussi is a named inventor on patents relating to stem cells: Isolated multipotent mesenchymal stem cell from human adult glomeruli, a method of preparing thereof and uses thereof in the regenerative medicine of the kidney, US2011256111 (A1), and, Use of microvesicles derived from stem cells for preparing a medicament for endo/epithelial regeneration of damaged or injured tissues or organs, and related in vitro and in vivo methods, ES2423483 (T3). L. Biancone declares no competing interests.
PowerPoint slides
Rights and permissions
About this article
Cite this article
Biancone, L., Camussi, G. Potential use of stem or progenitor cells for kidney regeneration. Nat Rev Nephrol 10, 67–68 (2014). https://doi.org/10.1038/nrneph.2013.257
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrneph.2013.257
This article is cited by
-
Cell and gene therapy for kidney disease
Nature Reviews Nephrology (2023)
-
Kidney-derived c-kit+ progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria
Scientific Reports (2018)
-
Hypoxic stress and IL-7 gene overexpression enhance the fusion potential of rat bone marrow mesenchymal stem cells with bovine renal epithelial cells
Molecular and Cellular Biochemistry (2015)
