Primary hyperoxaluria eventually leads to end-stage renal disease and systemic oxalosis; if left untreated, it may be fatal. The outcome might be different if primary hyperoxaluria is diagnosed early, but when is 'early'?
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References
Cochat, P. et al. Primary hyperoxaluria type 1: still challenging! Pediatr. Nephrol. 21, 1075–1081 (2006).
Monico, C. G., Olson, J. B. & Milliner, D. S. Implications of genotype and enzyme phenotype in pyridoxine response of patients with type I primary hyperoxaluria. Am. J. Nephrol. 25, 183–188 (2005).
Milliner, D. S. et al. Results of long-term treatment with orthophosphate and pyridoxine in patients with primary hyperoxaluria. N. Engl. J. Med. 331, 1553–1558 (1994).
Salido, E. C. et al. Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer. Proc. Natl Acad. Sci. USA 103, 18249–18254 (2006).
Fargue, S. et al. Effect of conservative treatment on the renal outcome of children with primary hyperoxaluria type 1. Kidney Int. 76, 767–773 (2009).
Hoppe, B. & Langman, C. B. A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria. Pediatr. Nephrol. 18, 986–991 (2003).
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Chand, A., Kaskel, F. Timely diagnosis of primary hyperoxaluria type 1. Nat Rev Nephrol 5, 670–671 (2009). https://doi.org/10.1038/nrneph.2009.186
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DOI: https://doi.org/10.1038/nrneph.2009.186
