●Six is seventh. Grimwood, J. & Schmutz, J. Nature 23 October (2003). A News and Views piece on what has been learnt from the finished sequence of human chromosome 6, which is published in the same issue. Nature has also launched its human chromosome web pages (available at http://www.nature.com/nature/focus/humangenome). The papers presented serve as the definitive historical record for the sequences and analyses of human chromosomes — the ultimate results of the Human Genome Project. All primary genome papers are available free online.

●The developmental role of serotonin: news from mouse molecular genetics. Gaspar, P. Cases, O. & Maroteaux, L. Nature Reviews Neuroscience December (2003) The revived interest in the role of serotonin in developmental processes, such as neurogenesis, apoptosis, axon branching and dendritogenesis, is discussed.

●Secrets of a porkier porker.Nature 23 October (2003) The finding that a single nucleotide can account for 15–30% of the muscle-mass variation in pigs is discussed in this News and Views article.

●Cancer pharmacogenetics: polymorphisms, pathways and beyond. Ulrich, C. M. Robien, K. & McLeod, H. Nature Reviews Cancer December (2003) A Review on the efforts to construct pathways of genes of pharmacological relevance for individual chemotherapeutics, and the promise of genetically guided cancer therapy.

●Neuropeptide gene polymorphisms and human behavioural disorders. Inui, A. Nature Reviews Drug Discovery December (2003)

●SARS — beginning to understand a new virus. Stadler, K., Masignani, V., Eickmann, M., Becker, S., Abrignani, S., Klenk, H.-D. & Rappuoli, R. Nature Reviews Microbiology December (2003) This Review details the genomics of the SARS coronavirus, its phylogeny, antigenic structure, immune response and potential therapeutic interventions.

●The rough guide to the genome.Nature 23 October (2003) The author of this News Feature profiles the international 'HapMap' project, which will produce a haplotype map based on the similarities in block structure and common haplotypes for the European, African and Asian populations. The project aims to provide a link between the DNA sequence of the genome and the way in which the genome influences the risk of disease.

●Getting to the end: telomerase access in yeast and humans. Vega, L. R., Mateyak, M. K. & Zakian, V. A. Nature Reviews Molecular Cell Biology December (2003)

●With your genes? Take one of these, three times a day.Nature 23 October (2003) A News Feature on the prospects of using genomic data to prescribe drugs.