Dose-response studies with patient-specific outcomes rather than surrogate measures of efficacy are needed to determine the benefits of vitamin D supplementation in the elderly. A novel study from Australia now casts doubt on the usefulness of intermittent, high-dose vitamin D supplementation as a strategy to reduce falls and fractures.
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Rosen, C. Vitamin D and falls—are intermittent, high doses better?. Nat Rev Endocrinol 7, 695–696 (2011). https://doi.org/10.1038/nrendo.2011.185
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DOI: https://doi.org/10.1038/nrendo.2011.185
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