Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Year in Review
  • Published:

Antiarrhythmic therapy in 2014

Contemporary approaches to treating arrhythmias

Nature Reviews Cardiology volume 12, pages 68–69 (2015)Cite this article

Subjects

Advances in treating cardiac arrhythmias include autonomic manipulation, drugs, imaging, devices, and genetics. I have selected articles published in 2014 that further our knowledge in each area, and which are representative of other important articles that could not be cited. Highlighting five diverse areas emphasizes the complexity of treating arrhythmias.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Advances in the treatment of arrhythmias.

References

  1. Remo, B. F. et al. Safety and efficacy of renal denervation as a novel treatment of ventricular tachycardia storm in patients with cardiomyopathy. Heart Rhythm 11, 541–546 (2014).

    Article  Google Scholar 

  2. Bhatt, D. et al. A controlled trial of renal denervation for resistant hypertension. N. Engl. J. Med. 370, 1393–1401 (2014).

    Article  CAS  Google Scholar 

  3. Premchand, R. K. et al. Autonomic regulation therapy via left or right cervical vagus nerve stimulation in patients with chronic heart failure: results of the ANTHEM-HF trial. J. Card. Fail. 20, 808–816 (2014).

    Article  Google Scholar 

  4. Scirica, B. M. et al. Effect of ranolazine on atrial fibrillation in patients with non-ST elevation acute coronary syndromes: observations from the MERLIN-TIMI 36 trial. Europace http://dx.doi.org/10.1093/europace/euu217.

  5. Antzelevitch C. et al. The role of late INa in development of cardiac arrhythmias. Handb. Exp. Pharmacol. 221, 137–168 (2014).

    Article  CAS  Google Scholar 

  6. Marrouche, N. F. et al. Association of atrial tissue fibrosis identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF study. JAMA 311, 498–506 (2014).

    Article  CAS  Google Scholar 

  7. Roes, S. D. et al. Infarct tissue heterogeneity assessed with contrast-enhanced MRI predicts spontaneous ventricular arrhythmia in patients with ischemic cardiomyopathy and implantable cardioverter-defibrillator. Circ. Cardiovasc. Imaging 2, 183–190 (2009).

    Article  Google Scholar 

  8. Ashikaga, H. et al. Feasibility of image-based simulation to estimate ablation target in human ventricular arrhythmia. Heart Rhythm 10, 1109–1116 (2013).

    Article  Google Scholar 

  9. Morillo, C. A. et al. Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of paroxysmal atrial fibrillation (RAAFT-2). JAMA 311, 692–700 (2014).

    Article  CAS  Google Scholar 

  10. Makita, N. et al. Novel calmodulin mutations associated with congenital arrhythmia susceptibility. Circ. Cardiovasc. Genet. 7, 466–474 (2014).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Indiana University School of Medicine, Krannert Institute of Cardiology, 1800 North Capitol Avenue, Indianapolis, 46202, IN, USA

    Douglas P. Zipes

Authors
  1. Douglas P. Zipes
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Douglas P. Zipes.

Ethics declarations

Competing interests

The author declares no competing financial interests.

PowerPoint slides

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zipes, D. Contemporary approaches to treating arrhythmias. Nat Rev Cardiol 12, 68–69 (2015). https://doi.org/10.1038/nrcardio.2014.211

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrcardio.2014.211

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing