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A tonic for anxiety

How do fundamental synaptic processes in specific neuron populations drive behavior? A new study links a reduction of tonic inhibitory GABA current in a subset of central amygdala neurons to anxiety after fear conditioning.

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Figure 1: The decrease in tonic inhibition of PKC+ neurons after fear conditioning generates anxiety.

Marinal Corral Spence/Nature Publishing Group

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Correspondence to Jaideep S Bains.

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Füzesi, T., Bains, J. A tonic for anxiety. Nat Neurosci 18, 1434–1435 (2015). https://doi.org/10.1038/nn.4118

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