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Putting a trace on metabolites

Abstract

Two independent groups describe isotopic labeling methods for detecting small-molecule metabolites for different applications.

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References

  1. Shanaiah, N. et al. Class selection of amino acid metabolites in body fluids using chemical derivatization and their enhanced 13C NMR. Proc. Natl. Acad. Sci. USA 104, 11540–11544 (2007).

    Article  CAS  Google Scholar 

  2. Yuan, J. et al. Kinetic flux profiling of nitrogen assimilation in Escherichia coli. Nat. Chem. Biol. 2, 529–530 (2006).

    Article  CAS  Google Scholar 

  3. Yuan, J. & Rabinowitz, J.D. Differentiating metabolites formed from de novo synthesis versus macromolecular decomposition. J. Am. Chem. Soc. 129, 9294–9295 (2007).

    Article  CAS  Google Scholar 

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Doerr, A. Putting a trace on metabolites. Nat Methods 4, 684–685 (2007). https://doi.org/10.1038/nmeth0907-684b

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  • DOI: https://doi.org/10.1038/nmeth0907-684b

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