A new carefully optimized and characterized genetically encoded fluorescent sensor for cyclic GMP (cGMP) has fast kinetics and properties that should make it an excellent compromise between sensitivity and specificity when compared to existing sensors.
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Jalink, K. Spying on cGMP with FRET. Nat Methods 3, 11–12 (2006). https://doi.org/10.1038/nmeth0106-11
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DOI: https://doi.org/10.1038/nmeth0106-11