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Where lies the blame for resistance—tumor or host?

Nature Medicine volume 13, pages 1144–1145 (2007)Cite this article

Cytokine signaling from the tumor microenvironment can allow leukemia cells to survive targeted imatinib therapy, in the first report of a non-autonomous resistance mechanism.

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Figure 1: Mechanisms of resistance to targeted cancer therapy.

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Authors and Affiliations

  1. Charles L. Sawyers is in the Human Oncology and Pathogenesis Program at the Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. sawyersc@mskcc.org,

    Charles L Sawyers

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  1. Charles L Sawyers
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Sawyers, C. Where lies the blame for resistance—tumor or host?. Nat Med 13, 1144–1145 (2007). https://doi.org/10.1038/nm1007-1144

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