This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Lapouge, G. et al. Identifying the cellular origin of squamous skin tumors. Proc. Natl. Acad. Sci. USA 108, 7431–7436 (2011).
White, A.C. et al. Defining the origins of Ras/p53-mediated squamous cell carcinoma. Proc. Natl. Acad. Sci. USA 108, 7425–7430 (2011).
Blanpain, C. & Fuchs, E. Epidermal homeostasis: a balancing act of stem cells in the skin. Nat. Rev. Mol. Cell Biol. 10, 207–217 (2009).
Greco, V. et al. A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell 4, 155–169 (2009).
Youssef, K.K. et al. Identification of the cell lineage at the origin of basal cell carcinoma. Nat. Cell Biol. 12, 299–305 (2010).
Wang, G.Y., Wang, J., Mancianti, M.-L. & Epstein, E.H. Jr. Basal cell carcinomas arise from hair follicle stem cells in Ptch+/− mice. Cancer Cell 19, 114–124 (2011).
Wakabayashi, Y., Mao, J.H., Brown, K., Girardi, M. & Balmain, A. Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice. Nature 445, 761–765 (2007).
Epstein, E.H. Jr. Mommy—where do tumors come from? J. Clin. Invest. 121, 1681–1683 (2011).
Chaffer, C.L. et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc. Natl. Acad. Sci. USA 108, 7950–7955 (2011).
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Tracing the roots of squamous cell carcinomas. Nat Med 17, 668–669 (2011). https://doi.org/10.1038/nm0611-668
Published:
Issue Date:
DOI: https://doi.org/10.1038/nm0611-668