An imaging technique adapted to differentiate between chronic obstructive pulmonary disease phenotypes can identify small-airway pathophysiology, locate the disease and potentially track disease progression. This approach may be used as a biomarker to identify the small-airway lesion in chronic obstructive pulmonary disease, at an individual level in the clinic (pages 1711–1715).
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Siddiqui, S., Usmani, O. Small airways, big challenge: measuring the unseen?. Nat Med 18, 1619–1621 (2012). https://doi.org/10.1038/nm.2981
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DOI: https://doi.org/10.1038/nm.2981