Specialized macrophage-like cells initiate antibody responses by trapping antigen in lymph. These antigen-trapping cells are located in the migration pathway of recirculating B cells, which can engage the trapped antigen.
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MacLennan, I. Holding antigen where B cells can find it. Nat Immunol 8, 909–910 (2007). https://doi.org/10.1038/ni0907-909
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DOI: https://doi.org/10.1038/ni0907-909
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