Chemokines 'trigger' the integrin LFA-1 to different conformational and affinity states. Elegant experiments provide new insights into the involvement of different LFA-1 affinity states in rapid lymphocyte arrest under flow.
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Laudanna, C. Integrin activation under flow: a local affair. Nat Immunol 6, 429–430 (2005). https://doi.org/10.1038/ni0505-429
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DOI: https://doi.org/10.1038/ni0505-429
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