The ability of natural killer cells to eliminate abnormal cells has been shown to be enhanced by triggering of certain inhibitory receptors during their maturation. New data show that sometimes the opposite can happen.
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NK cell education via nonclassical MHC and non-MHC ligands
Cellular & Molecular Immunology Open Access 06 June 2016
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Cruz-Munoz, ME., Veillette, A. Do NK cells always need a license to kill?. Nat Immunol 11, 279–280 (2010). https://doi.org/10.1038/ni0410-279
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DOI: https://doi.org/10.1038/ni0410-279
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