Either stimulation of the innate immune system or infection can result in transient focal inflammatory structures in the liver. Such structures can promote further proliferation of already activated cytotoxic T lymphocytes and enhance antipathogen immunity.
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Crispe, I., Pierce, R. Killer T cells find meaningful encounters through iMATEs. Nat Immunol 14, 533–534 (2013). https://doi.org/10.1038/ni.2620
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DOI: https://doi.org/10.1038/ni.2620