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Killer T cells find meaningful encounters through iMATEs

Either stimulation of the innate immune system or infection can result in transient focal inflammatory structures in the liver. Such structures can promote further proliferation of already activated cytotoxic T lymphocytes and enhance antipathogen immunity.

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Figure 1: The iMATE concept.

Katie Vicari

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Correspondence to Ian N Crispe.

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Crispe, I., Pierce, R. Killer T cells find meaningful encounters through iMATEs. Nat Immunol 14, 533–534 (2013). https://doi.org/10.1038/ni.2620

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