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Viral RNA gymnastics

Retroviruses have a stretch of RNA that dimerizes during viral particle formation. A new study suggests that RNA flexibility in the monomeric form may facilitate dimerization or other RNA-dependent viral functions.

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Figure 1: A general view of structural rearrangements of retroviral dimerization elements.

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Calabro, V., Frankel, A. Viral RNA gymnastics. Nat Chem Biol 1, 67–68 (2005). https://doi.org/10.1038/nchembio0705-67

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