Recently developed advanced microfluidics-based systems have outperformed known screening tools with respect to throughput, flexibility, sensitivity and tricks for hit recovery. This has enabled the discovery of novel and improved proteins from random mutagenesis libraries or metagenome-based sources.
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Bornscheuer, U. Beating the odds. Nat Chem Biol 12, 54–55 (2016). https://doi.org/10.1038/nchembio.1989
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DOI: https://doi.org/10.1038/nchembio.1989