Reactants require a certain amount of energy to react — but what kind of energy? Chemical dynamics simulations predict that vibrationally exciting reactants can promote 1,3-dipolar cycloaddition reactions by bending them into the correct transition state shape.
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Barnes, G., Hase, W. Bent out of shape. Nature Chem 1, 103–104 (2009). https://doi.org/10.1038/nchem.193
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DOI: https://doi.org/10.1038/nchem.193
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