High-throughput screening using an in vivo infection model identifies nontraditional antimicrobials.
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References
Brown, E.D. & Wright, G.D. Chem. Rev. 105, 759–774 (2005).
Moy, T.I. et al. Proc. Natl. Acad. Sci. USA 103, 10414–10419 (2006).
Hung, D.T., Shakhnovich, E.A., Pierson, E & Mekalanos, J.J. Science 310, 670–674 (2005).
Kauppi, A.M et al. Chem. Biol. 10, 241–249 (2003).
Gauthier, A. et al. Antimicrob. Agents Chemother. 49, 4101–4109 (2005).
Nordfelth, R. et al. Infect. Immun. 73, 3104–3114 (2005).
Li, X. et al. Chem. Biol. 11, 1423–1430 (2004).
Wang, J. et al. Nature 441, 358–361 (2006).
Kwok, T.C.Y. et al. Nature 441, 91–95 (2006).
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Bhavsar, A., Brown, E. The worm turns for antimicrobial discovery. Nat Biotechnol 24, 1098–1100 (2006). https://doi.org/10.1038/nbt0906-1098
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DOI: https://doi.org/10.1038/nbt0906-1098
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