Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Discovery of MRSA active antibiotics using primary sequence from the human microbiome

Chu, J. et al. Nat. Chem. Biol. 12, 1004–1006 (2016)

Cell-type-specific optical recording of membrane voltage dynamics in freely moving mice

Marshall, J.D. et al. Cell 167, 1650–1662.e15 (2016)

Generation of influenza A viruses as live but replication-incompetent virus vaccines

Si, L. et al. Science 354, 1170–1173 (2016)

Genetic drivers of epigenetic and transcriptional variation in human immune cells

Chen, L. et al. Cell 167, 1398–1414.e24 (2016)

Phantom motor execution facilitated by machine learning and augmented reality as treatment for phantom limb pain: a single group, clinical trial in patients with chronic intractable phantom limb pain

Ortiz-Catalan, M. et al. Lancet 10.1016/S0140-6736(16)31598-7 (2016)