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Increased phosphorus content of preload suppresses ad libitum energy intake at subsequent meal

International Journal of Obesity volume 34, pages 1446–1448 (2010)Cite this article

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Abstract

Food intake is believed to be partially controlled by hepatic signals related to adenosine triphosphate (ATP) status. We hypothesized that increased phosphorus content of one meal can stimulate hepatic ATP synthesis of the next meal, which in turn contributes to satiation. This hypothesis was tested by measuring the energy intake after phosphorus addition to several preloads. The phosphorus content of the different preloads was found to be inversely related to the energy intake at a subsequent meal, although the exact mechanism behind such effects was not studied. Such findings point to a potential role for phosphorus in the control of food intake.

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Acknowledgements

We thank the following students for their support in the recruitment and execution of the different experiments: L Hamoud, R Kamal, R Housari, T Tabbakh, M Al-Dirani and F Mazloum.

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  1. Department of Nutrition and Food Science, Faculty of Agricultural and Food Sciences, American University of Beirut, Beirut, Lebanon

    O A Obeid, S Dimachkie & S Hlais

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  1. O A Obeid
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  2. S Dimachkie
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  3. S Hlais
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Correspondence to O A Obeid.

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Obeid, O., Dimachkie, S. & Hlais, S. Increased phosphorus content of preload suppresses ad libitum energy intake at subsequent meal. Int J Obes 34, 1446–1448 (2010). https://doi.org/10.1038/ijo.2010.74

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  • DOI: https://doi.org/10.1038/ijo.2010.74

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