Abstract
Comparison of percent fat mass across different body composition analysis devices is important given variation in technology accuracy and precision, as well as the growing need for cross-validation of devices often applied across longitudinal studies. We compared EchoMRI-AH and Lunar iDXA quantification of percent body fat (PBF) in 84 adults (43M, 41F), with the mean age 39.7±15.9 years and body mass index (BMI) 26.2±5.3 kg/m2. PBF correlated strongly between devices (r>0.95, P<0.0001). A prediction equation was derived in half of the subjects, and the other half were used to cross-validate the proposed equation (EchoMRI-AH PBF=[(0.94 × iDXA PBF)+(0.14 × Age)+(3.3 × Female)–8.83). The mean PBF difference (predicted-measured) in the validation group was not different from 0 (diff=0.27%, 95% confidence interval: −0.42–0.96, P=0.430). Bland–Altman plots showed a bias with higher measured PBF on EchoMRI-AH versus iDXA in all 84 subjects (β=0.13, P<0.0001). The proposed prediction equation was valid in our cross-validation sample, and it has the potential to be applied across multicenter studies.
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Acknowledgements
This work was partially supported by a NORC Center Grant #P30DK072476 (ER). The EchoMRI-AH instrument was provided to PBRC as a gift to the institution.
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Marlatt, K., Greenway, F. & Ravussin, E. Assessment of EchoMRI-AH versus dual-energy X-ray absorptiometry by iDXA to measure human body composition. Eur J Clin Nutr 71, 558–560 (2017). https://doi.org/10.1038/ejcn.2016.236
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DOI: https://doi.org/10.1038/ejcn.2016.236