Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Regenerative medicine

Interspecies pancreas transplants

Nature volume 542, pages 168–169 (2017)Cite this article

Subjects

A mouse pancreas grown in a rat controls blood-sugar levels when transplanted into a mouse that models type 1 diabetes. This achievement provides a tantalizing glimpse of how organs could be grown for therapeutic use. See Article p.191

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: A rat-grown mouse pancreas to treat diabetic mice.

Notes

  1. See all news & views

References

  1. Yamaguchi, T. et al. Nature 542, 191–196 (2017).

    Article  CAS  ADS  Google Scholar 

  2. Clevers, H. Cell 165, 1586–1597 (2016).

    Article  CAS  Google Scholar 

  3. Rashid, T., Kobayashi, T. & Nakauchi, H. Cell Stem Cell 15, 406–409 (2014).

    Article  CAS  Google Scholar 

  4. Kobayashi, T. et al. Cell 142, 787–799 (2010).

    Article  CAS  Google Scholar 

  5. Offield, M. F. et al. Development 122, 983–995 (1996).

    Article  CAS  Google Scholar 

  6. Bluestone, J. A., Herold, K. & Eisenbarth, G. Nature 464, 1293–1300 (2010).

    Article  CAS  ADS  Google Scholar 

  7. McMahon, A. P. Curr. Top. Dev. Biol. 117, 31–64 (2016).

    Article  Google Scholar 

  8. Srivastava, D. Cell 126, 1037–1048 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Qiao Zhou is in the Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts 02138, USA.,

    Qiao Zhou

Authors
  1. Qiao Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Qiao Zhou.

Related links

Related links

Related links in Nature Research

In retrospect: Thirty-five years of endless cell potential

Diabetes: A smart insulin patch

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhou, Q. Interspecies pancreas transplants. Nature 542, 168–169 (2017). https://doi.org/10.1038/nature21490

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature21490

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research