Telomerase synthesizes DNA sequences that protect the integrity of chromosome ends. A model for how the components of this enzyme complex co-assemble offers insight into its structure and function. See Article p.187
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Notes
*This article and the paper5 under discussion were published online on 3 April 2013.
References
Olovnikov, A. M. J. Theor. Biol. 41, 181–190 (1973).
Harley, C. B., Futcher, A. B. & Greider, C. W. Nature 345, 458–460 (1990).
Greider, C. W. & Blackburn, E. H. Cell 43, 405–413 (1985).
Kim, N. W. et al. Science 266, 2011–2015 (1994).
Jiang, J. et al. Nature 496, 187–192 (2013).
Mason, M., Schuller, A. & Skordalakes, E. Curr. Opin. Struct. Biol. 21, 92–100 (2011).
Theimer, C. A. & Feigon, J. Curr. Opin. Struct. Biol. 16, 307–318 (2006).
Min, B. & Collins, K. Mol. Cell 36, 609–619 (2009).
Sauerwald, A. et al. Nature Struct. Mol. Biol. 20, 454–460 (2013).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Akiyama, B., Stone, M. A solution to the telomerase puzzle. Nature 496, 177–178 (2013). https://doi.org/10.1038/nature12090
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature12090