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Trove of CRISPR-like gene-cutting enzymes found in microbes

The search for a CRISPR enzyme’s ancestors has revealed more than one million potential genome-editing tools.
  1. Heidi Ledford
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By exploring the evolutionary origins of an enzyme used in the CRISPR genome-editing system, researchers have unearthed more than one million other potential editors lurking in microbial genomes.

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doi: https://doi.org/10.1038/d41586-021-02461-2

Updates & Corrections

  • Correction 16 September 2021: An earlier version of this story stated that researchers had not seen CRISPR activity in eukaryotic cells before. This quote has been amended to say that a CRISPR-like system had not been previously seen in eukaryotes.

References

  1. Altae-Tran, H. et al. Science https://doi.org/10.1126/science.abj6856 (2021).

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