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Masahiro Fujita in a hospital bed, with a breathing tube. In front of him is a monitor plastered with Japanese signs.

People with paralysing conditions such as motor-neuron disease often rely on technology to help them speak.Credit: BJ Warnick/Alamy

Brain signals translated into speech

In an effort to provide a voice for people who can’t speak, neuroscientists have designed a device that can transform brain signals into speech using artificial intelligence. The technology can synthesize whole sentences that are mostly intelligible — although it isn’t yet accurate enough to use outside the lab. Researchers trained the system with five volunteers who read hundreds of sentences aloud while their brain activity was recorded by electrodes.

Hear two sentences compared to their dopplegangers generated from brain activity (MP3 audio file).

Nature | 4 min read

Reference: Nature paper

Go deeper: Read what the experts think in the News & Views article

Killer pig virus spurs vaccine research

A highly contagious disease that kills pigs has swept through China, the world’s largest pig producer. African swine fever was detected in China only last August, but there have since been at least 120 outbreaks — and the virus is already moving through neighbouring countries. Under intense political pressure, scientists in China are ramping up efforts to study the virus and produce a vaccine.

Nature | 6 min read

FEATURES & OPINION

Science in transition

For transgender people choosing medical gender transition, the long-term health effects of hormone treatment have long been unknown. Now, a wave of studies is focusing on its impacts on everything from mental health and well-being to the potential of increased cancer risks. The largest ever such study, involving 2,600 transgender participants in Europe, has published its first results — and the research could last several lifetimes.

Nature | 16 min read

Rein in the four horsemen of irreproducibility

Experimental psychologist Dorothy Bishop names the four horsemen of the reproducibility apocalypse: publication bias, low statistical power, P-value hacking and HARKing (hypothesizing after results are known). “My generation and the one before us have done little to rein these in,” argues Bishop — but change is coming.

Nature | 5 min read

150 YEARS OF NATURE

Illustration and quote from James Clerk Maxwell

In 1875, James Clerk Maxwell wrote about the thermodynamic evidence for molecules. Read part one here. (Part two was published a week later.)

150 years at the heart of science

As part of Nature’s 150th anniversary, we’re showcasing 150 articles from the archive, one for each year the journal has been published. Not a definitive list of top research, but a selection of interesting, illuminating, entertaining and sometimes controversial articles selected by the editors through discussion and debate. We'll be posting one article per day over the 150 days leading up to our anniversary issue on 7 November.

Facebook | An enlightening scroll

A diving penguin reflected in the water’s surface

A penguin dives into its pool in the zoo in Kronberg, Germany.Michael Probst/AP/Shutterstock