Abstract
We provide characterization of a highly polymorphic dinucleotide repeat in the human TNF-receptor 1 gene (TNFR1, TNFRp55, CD120a). We have observed 11 alleles at this locus in individuals from the West of Scotland. In a panel of healthy, unrelated individuals from the West of Scotland (n = 143), the overall heterozygosity was 68% , indicating the potential usefulness of these markers in immunogenetic studies.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 6 digital issues and online access to articles
$119.00 per year
only $19.83 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Eskdale, J., Turestkaya, R., Armstrong, C. et al. A polymorphic microsatellite marker in the human p55 TNF receptor, CD120a. Genes Immun 1, 228–230 (2000). https://doi.org/10.1038/sj.gene.6363663
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.gene.6363663
Keywords
This article is cited by
-
Segregation of HLA/TNF region is linked to leprosy clinical spectrum in families displaying mixed leprosy subtypes
Genes & Immunity (2003)
-
Cytokine gene polymorphism in human disease: on-line databases, Supplement 2
Genes & Immunity (2002)